| Gene Information | |
|---|---|
| Gene Name | RAB11FIP4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 637 |
| Protein Names | Rab11 family-interacting protein 4 (FIP4-Rab11) (Rab11-FIP4) (Arfophilin-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000131242 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q86YS3 |
| Gene Card | RAB11FIP4 |
| Uniprot ID | Q86YS3 |
| Pfam | PF09457 |
| In ASD | no |
| Allosteric Prediction | no (-1.067597043) |
| Ortholog in Animals | Alpaca_ RAB11FIP4 ( ortholog_one2one ) Dog_ RAB11FIP4 ( ortholog_one2one ) GuineaPig_ RAB11FIP4 ( ortholog_one2one ) Macaque_ RAB11FIP4 ( ortholog_one2one ) Mouse_ Rab11fip4 ( ortholog_one2one ) Pig_ RAB11FIP4 ( ortholog_one2one ) Rat_ Rab11fip4 ( ortholog_one2one ) Rabbit_ RAB11FIP4 ( ortholog_one2one ) |
| Ohnologs | RAB11FIP3 |
| Paralogs | RAB11FIP3 |
| Tissue | NA |
| Tissue Specificity | Present at high level in testis (at protein level). Weakly expressed in other tissues. {ECO:0000269|PubMed:12857874}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endosome {ECO:0000269|PubMed:20682791}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:12857874}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:12857874}. Recycling endosome membrane {ECO:0000269|PubMed:15601896}; Peripheral membrane protein. Cleavage furrow {ECO:0000269|PubMed:15601896}. Midbody {ECO:0000269|PubMed:12857874, ECO:0000269|PubMed:15601896}. Cytoplasmic vesicle {ECO:0000269|PubMed:15601896}. Note=Recruited to the cleavage furrow and the midbody during cytokinesis. {ECO:0000269|PubMed:15601896}. |
| Mouse PG classification | NA |
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