| Gene Information | |
|---|---|
| Gene Name | QTRT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 403 |
| Protein Names | Queuine tRNA-ribosyltransferase catalytic subunit 1 (EC 2.4.2.64) (Guanine insertion enzyme) (tRNA-guanine transglycosylase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000213339 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9BXR0 |
| Gene Card | QTRT1 |
| Uniprot ID | Q9BXR0 |
| Pfam | PF01702 |
| In ASD | no |
| Allosteric Prediction | no (-0.656551994) |
| Ortholog in Animals | Alpaca_ QTRT1 ( ortholog_one2one ) GuineaPig_ QTRT1 ( ortholog_one2one ) Macaque_ QTRT1 ( ortholog_one2one ) Mouse_ Qtrt1 ( ortholog_one2one ) Pig_ QTRT1 ( ortholog_one2one ) Rat_ Qtrt1 ( ortholog_one2one ) Rabbit_ QTRT1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | QTRT2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.04(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6H42 (X-ray 2.45A ) 6H45 (X-ray 2.40A ) 7NQ4 (X-ray 2.88A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03218}. Mitochondrion outer membrane {ECO:0000255|HAMAP-Rule:MF_03218}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_03218}; Cytoplasmic side {ECO:0000255|HAMAP-Rule:MF_03218}. Note=Weakly associates with mitochondria, possibly via QTRT2. {ECO:0000255|HAMAP-Rule:MF_03218}. |
| Mouse PG classification | NA |
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