| Gene Information | |
|---|---|
| Gene Name | PRKAR1B |
| Organism | Homo sapiens (Human) |
| Gene Length | 381 |
| Protein Names | cAMP-dependent protein kinase type I-beta regulatory subunit |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000188191 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P31321 |
| Gene Card | PRKAR1B |
| Uniprot ID | P31321 |
| Pfam | PF00027; PF02197 |
| In ASD | no |
| Allosteric Prediction | yes (0.501293814) |
| Ortholog in Animals | Alpaca_ PRKAR1B ( ortholog_one2one ) Dog_ PRKAR1B ( ortholog_one2one ) GuineaPig_ PRKAR1B ( ortholog_one2one ) Macaque_ PRKAR1B ( ortholog_one2one ) Mouse_ Prkar1b ( ortholog_one2one ) Pig_ PRKAR1B ( ortholog_one2one ) Rat_ Prkar1b ( ortholog_one2one ) |
| Ohnologs | PRKAR1A |
| Paralogs | PRKAR2A, CNBD1, PRKAR2B, PRKAR1A |
| Tissue | NA |
| Tissue Specificity | Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 4DIN (X-ray 3.70A ) 4F9K (X-ray 2.80A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:23115245}. |
| Mouse PG classification | NA |
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