| Gene Information | |
|---|---|
| Gene Name | ADAMTS20 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1910 |
| Protein Names | A disintegrin and metalloproteinase with thrombospondin motifs 20 (ADAM-TS 20) (ADAM-TS20) (ADAMTS-20) (EC 3.4.24.-) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000173157 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P59510 |
| Gene Card | ADAMTS20 |
| Uniprot ID | P59510 |
| Pfam | PF17771; PF19236; PF05986; PF08685; PF01562; PF01421; PF00090 |
| In ASD | no |
| Allosteric Prediction | no (-0.893948694) |
| Ortholog in Animals | Alpaca_ ADAMTS20 ( ortholog_one2one ) Dog_ ADAMTS20 ( ortholog_one2one ) GuineaPig_ ADAMTS20 ( ortholog_one2one ) Macaque_ ADAMTS20 ( ortholog_one2one ) Mouse_ Adamts20 ( ortholog_one2one ) Pig_ ADAMTS20 ( ortholog_one2one ) Rat_ Adamts20 ( ortholog_one2one ) Rabbit_ ADAMTS20 ( ortholog_one2one ) |
| Ohnologs | ADAMTS9 |
| Paralogs | ADAMTS5, ADAMTSL2, ADAMTS15, ADAMTS4, ADAMTS1, ADAMTS19, ADAMTS8, ADAMTSL3, ADAMTS7, THSD4, ADAMTSL4, ADAMTS3, ADAMTS6, ADAMTSL5, ADAMTS9, ADAMTS12, ADAMTS14, ADAMTS13, ADAMTSL1, ADAMTS10, ADAMTS16, ADAMTS17, PAPLN, ADAMTS2, ADAMTS18 |
| Tissue | NA |
| Tissue Specificity | Very sparingly expressed, although is detected at low levels in testis, prostate, ovary, heart, placenta, lung and pancreas. Overexpressed in several brain, colon and breast carcinomas. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs7302446 rs7297737 rs7310011 |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix {ECO:0000250}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |