| Gene Information | |
|---|---|
| Gene Name | CERS2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 380 |
| Protein Names | Ceramide synthase 2 (CerS2) (LAG1 longevity assurance homolog 2) (SP260) (Sphingosine N-acyltransferase CERS2) (EC 2.3.1.24) (Tumor metastasis-suppressor gene 1 protein) (Very-long-chain ceramide synthase CERS2) (EC 2.3.1.297) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000143418 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96G23 |
| Gene Card | CERS2 |
| Uniprot ID | Q96G23 |
| Pfam | PF00046; PF03798 |
| In ASD | no |
| Allosteric Prediction | no (-0.280470193) |
| Ortholog in Animals | Alpaca_ CERS2 ( ortholog_one2one ) Dog_ CERS2 ( ortholog_one2one ) GuineaPig_ CERS2 ( ortholog_one2one ) Macaque_ CERS2 ( ortholog_one2one ) Mouse_ Cers2 ( ortholog_one2one ) Pig_ CERS2 ( ortholog_one2one ) Rat_ Cers2 ( ortholog_one2one ) Rabbit_ CERS2 ( ortholog_one2one ) |
| Ohnologs | CERS4, CERS5, CERS3 |
| Paralogs | CERS3, CERS4, CERS5, CERS6, CERS1 |
| Tissue | NA |
| Tissue Specificity | Expressed in kidney, liver, brain, heart, placenta and lung. {ECO:0000269|PubMed:11543633}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs267738 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:18165233}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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