| Gene Information | |
|---|---|
| Gene Name | PYHIN1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 492 |
| Protein Names | Pyrin and HIN domain-containing protein 1 (Interferon-inducible protein X) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 78 ( ENSG00000163564 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q6K0P9 |
| Gene Card | PYHIN1 |
| Uniprot ID | Q6K0P9 |
| Pfam | PF02760; PF02758 |
| In ASD | no |
| Allosteric Prediction | no (-1.000028531) |
| Ortholog in Animals | Alpaca_ PYHIN1 ( ortholog_one2one ) Macaque_ PYHIN1 ( ortholog_one2one ) Mouse_ Ifi208 ( ortholog_many2many ) Mouse_ Ifi214 ( ortholog_many2many ) Mouse_ Ifi213 ( ortholog_many2many ) Rat_ RGD1562462 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | IFI16, MNDA, AIM2 |
| Tissue | lymph.node, spleen, appendix, lung |
| Tissue Specificity | Expressed in spleen, lymph node and peripheral blood leukocytes, and at lower levels in thymus, bone marrow and fetal liver. Down-regulated in breast tumors. {ECO:0000269|PubMed:15122330}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | [Isoform 1]: Nucleus, nucleoplasm.; [Isoform 3]: Nucleus, nucleoplasm.; [Isoform 5]: Nucleus. Nucleus speckle. |
| Mouse PG classification | NA |
| click here to return to the previous page | |