| Gene Information | |
|---|---|
| Gene Name | PCARE |
| Organism | Homo sapiens (Human) |
| Gene Length | 1288 |
| Protein Names | Photoreceptor cilium actin regulator |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 36 ( ENSG00000179270 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | A6NGG8 |
| Gene Card | PCARE |
| Uniprot ID | A6NGG8 |
| Pfam | PF15449 |
| In ASD | no |
| Allosteric Prediction | no (-1.188921358) |
| Ortholog in Animals | Alpaca_ PCARE ( ortholog_one2one ) Dog_ PCARE ( ortholog_one2one ) GuineaPig_ PCARE ( ortholog_one2one ) Macaque_ PCARE ( ortholog_one2one ) Mouse_ Pcare ( ortholog_one2one ) Pig_ PCARE ( ortholog_one2one ) Rat_ Pcare ( ortholog_one2one ) Rabbit_ PCARE ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Specifically expressed in retina. {ECO:0000269|PubMed:20398884}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7LXF (X-ray 1.65A ) |
| DBSNP | rs10084168 rs267606690 rs114057537 rs77828062 rs77003681 rs116156338 rs1572829341 rs374283240 rs201284350 rs201900716 rs17007544 rs10166913 rs200758183 rs140776870 rs571059484 rs149601594 rs17744093 rs182248363 rs758883789 rs184249075 rs192350796 rs200367963 rs766723736 rs182812191 rs375826049 rs187333111 rs1975713 |
| Subcellular location [CC] | Cell projection, cilium, photoreceptor outer segment {ECO:0000269|PubMed:20398886}. Photoreceptor inner segment {ECO:0000250|UniProtKB:Q6PAC4}. |
| Mouse PG classification | NA |
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