| Gene Information | |
|---|---|
| Gene Name | LPCAT3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 487 |
| Protein Names | Lysophospholipid acyltransferase 5 (LPLAT 5) (EC 2.3.1.-) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.n7) (1-acylglycerophosphoserine O-acyltransferase) (EC 2.3.1.n6) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lyso-PC acyltransferase) (Lysophosphatidylcholine acyltransferase 3) (Lyso-PC acyltransferase 3) (Lysophosphatidylserine acyltransferase) (LPSAT) (Lyso-PS acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 5) (O-acyltransferase domain-containing protein 5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000111684 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q6P1A2 |
| Gene Card | LPCAT3 |
| Uniprot ID | Q6P1A2 |
| Pfam | PF03062 |
| In ASD | no |
| Allosteric Prediction | no (-0.543228646) |
| Ortholog in Animals | Alpaca_ LPCAT3 ( ortholog_one2one ) Dog_ LPCAT3 ( ortholog_one2one ) GuineaPig_ LPCAT3 ( ortholog_one2one ) Macaque_ LPCAT3 ( ortholog_one2one ) Mouse_ Lpcat3 ( ortholog_one2one ) Pig_ LPCAT3 ( ortholog_one2one ) Rat_ Lpcat3 ( ortholog_one2one ) Rabbit_ LPCAT3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MBOAT7, PORCN, MBOAT1, MBOAT4, MBOAT2 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in liver, pancreas and adipose tissue. Very low expression in skeletal muscle and heart. Detected in neutrophils. {ECO:0000269|PubMed:18195019, ECO:0000269|PubMed:18772128}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34196984 rs1984564 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:18195019}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |