Gene Information
Gene NamePVR
OrganismHomo sapiens (Human)
Gene Length417
Protein NamesPoliovirus receptor (Nectin-like protein 5) (NECL-5) (CD antigen CD155)
Target Namepoliovirus receptor
Target TypeNA
Gene Age132 ( ENSG00000073008 )
Evolutionary StageEumetazoa
AlphaFoldDBP15151
Gene CardPVR
Uniprot IDP15151
PfamPF08205; PF07686
In ASDno
Allosteric Predictionno (-0.397661351)
Ortholog in AnimalsAlpaca_ PVR ( ortholog_one2one )
Dog_ PVR ( ortholog_one2one )
Mouse_ Pvr ( ortholog_one2one )
Rat_ Pvr ( ortholog_one2one )
OhnologsNECTIN1, NECTIN4, CADM3, CADM2, NECTIN3
ParalogsTIGIT, NCR3, CD200, NECTIN1, NECTIN2, CADM3, NECTIN4, CADM2, CRTAM, NECTIN3, CADM4, SMAGP, CADM1, CD226
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1DGI  (EM  22.00A  )  1NN8  (EM  15.00A  )  3EPC  (EM  8.00A  )  3EPD  (EM  9.00A  )  3EPF  (EM  9.00A  )  3J8F  (EM  3.70A  )  3J9F  (EM  9.00A  )  3UDW  (X-ray  2.90A  )  3URO  (X-ray  3.50A  )  4FQP  (X-ray  3.60A  )  6ARQ  (X-ray  2.88A  )  6ISC  (X-ray  2.20A  )  6O3O  (X-ray  2.80A  ) 
DBSNP rs1058402  rs35365841  rs203710 
Subcellular location [CC][Isoform Alpha]: Cell membrane;
Single-pass type I membrane protein.;
[Isoform Delta]: Cell membrane;
Single-pass type I membrane protein.;
[Isoform Beta]: Secreted.;
[Isoform Gamma]: Secreted.
Mouse PG classificationNA
click here to return to the previous page