| Gene Information | |
|---|---|
| Gene Name | PUS3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 481 |
| Protein Names | tRNA pseudouridine(38/39) synthase (EC 5.4.99.45) (tRNA pseudouridine synthase 3) (tRNA pseudouridylate synthase 3) (tRNA-uridine isomerase 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000110060 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9BZE2 |
| Gene Card | PUS3 |
| Uniprot ID | Q9BZE2 |
| Pfam | PF01416 |
| In ASD | no |
| Allosteric Prediction | no (-1.775140094) |
| Ortholog in Animals | Alpaca_ PUS3 ( ortholog_one2one ) Dog_ PUS3 ( ortholog_one2one ) GuineaPig_ PUS3 ( ortholog_one2one ) Macaque_ PUS3 ( ortholog_one2one ) Mouse_ Pus3 ( ortholog_one2one ) Pig_ PUS3 ( ortholog_one2one ) Rat_ Pus3 ( ortholog_one2one ) Rabbit_ PUS3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PUS1, PUSL1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs622756 rs549990 rs3088241 |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
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