| Gene Information | |
|---|---|
| Gene Name | PTTG |
| Organism | Homo sapiens (Human) |
| Gene Length | 202 |
| Protein Names | Securin (Esp1-associated protein) (Pituitary tumor-transforming gene 1 protein) (Tumor-transforming protein 1) (hPTTG) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O95997 |
| Gene Card | PTTG1 |
| Uniprot ID | O95997 |
| Pfam | PF04856 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed at low level in most tissues, except in adult testis, where it is highly expressed. Overexpressed in many patients suffering from pituitary adenomas, primary epithelial neoplasias, and esophageal cancer. {ECO:0000269|PubMed:9811450}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.004626(Rat);0.020000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7NJ0 (EM 3.60A ) 7NJ1 (EM 2.90A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm. Nucleus. |
| Mouse PG classification | NA |
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