Gene Information
Gene NamePTS
OrganismHomo sapiens (Human)
Gene Length145
Protein Names6-pyruvoyl tetrahydrobiopterin synthase (PTP synthase) (PTPS) (EC 4.2.3.12)
Target Name6-pyruvoyl tetrahydrobiopterin synthase
Target TypeNA
Gene Age680 ( ENSG00000150787 )
Evolutionary StageCellular_organisms
AlphaFoldDBQ03393
Gene CardPTS
Uniprot IDQ03393
PfamPF01242
In ASDno
Allosteric Predictionyes (0.18909505)
Ortholog in AnimalsAlpaca_ PTS ( ortholog_one2one )
GuineaPig_ PTS ( ortholog_one2one )
Macaque_ PTS ( ortholog_one2one )
Mouse_ Pts ( ortholog_one2one )
Pig_ PTS ( ortholog_one2one )
Rat_ Pts ( ortholog_one2one )
Rabbit_ PTS ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 3I2B  (X-ray  2.30A 
DBSNP rs104894274  rs1167104933  rs104894273  rs1317230624  rs1328320990  rs1449216377  rs104894278  rs104894275  rs104894277  rs770387277  rs370340361  rs1592880489  rs765406631  rs104894276  rs104894280  rs750455879  rs1555198458  rs200712908  rs1555198495  rs104894279  rs150726932  rs1040441824  rs1859972447 
Subcellular location [CC]NA
Mouse PG classificationHPG
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