| Gene Information | |
|---|---|
| Gene Name | ARR3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 388 |
| Protein Names | Arrestin-C (Cone arrestin) (C-arrestin) (cArr) (Retinal cone arrestin-3) (X-arrestin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000120500 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | P36575 |
| Gene Card | ARR3 |
| Uniprot ID | P36575 |
| Pfam | PF02752; PF00339 |
| In ASD | no |
| Allosteric Prediction | yes (0.0563996) |
| Ortholog in Animals | Alpaca_ ARR3 ( ortholog_one2one ) Dog_ ARR3 ( ortholog_one2one ) Macaque_ ARR3 ( ortholog_one2one ) Mouse_ Arr3 ( ortholog_one2one ) Pig_ ARR3 ( ortholog_one2one ) Rat_ Arr3 ( ortholog_one2one ) Rabbit_ ARR3 ( ortholog_one2one ) |
| Ohnologs | SAG, ARRB1, ARRB2 |
| Paralogs | SAG, ARRB1, ARRB2 |
| Tissue | NA |
| Tissue Specificity | Inner and outer segments, and the inner plexiform regions of the retina. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.025(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11548182 rs1555941116 rs765658563 |
| Subcellular location [CC] | Photoreceptor inner segment {ECO:0000250|UniProtKB:Q9EQP6}. Cell projection, cilium, photoreceptor outer segment {ECO:0000250|UniProtKB:Q9EQP6}. |
| Mouse PG classification | NA |
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