| Gene Information | |
|---|---|
| Gene Name | FNTA |
| Organism | Homo sapiens (Human) |
| Gene Length | 379 |
| Protein Names | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha) |
| Target Name | protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000168522 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P49354 |
| Gene Card | FNTA |
| Uniprot ID | P49354 |
| Pfam | PF01239 |
| In ASD | no |
| Allosteric Prediction | yes (0.545792545) |
| Ortholog in Animals | Alpaca_ FNTA ( ortholog_one2one ) GuineaPig_ FNTA ( ortholog_one2one ) Mouse_ Fnta ( ortholog_one2one ) Pig_ FNTA ( ortholog_one2one ) Rat_ Fnta ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RABGGTA, PTAR1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1JCQ (X-ray 2.30A ) 1LD7 (X-ray 2.00A ) 1LD8 (X-ray 1.80A ) 1MZC (X-ray 2.00A ) 1S63 (X-ray 1.90A ) 1SA4 (X-ray 2.10A ) 1TN6 (X-ray 1.80A ) 2F0Y (X-ray 2.70A ) 2H6F (X-ray 1.50A ) 2H6G (X-ray 1.85A ) 2H6H (X-ray 1.80A ) 2H6I (X-ray 3.00A ) 2IEJ (X-ray 1.80A ) 3E37 (X-ray 1.80A ) |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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