| Gene Information | |
|---|---|
| Gene Name | POLR2M |
| Organism | Homo sapiens (Human) |
| Gene Length | 368 |
| Protein Names | DNA-directed RNA polymerase II subunit GRINL1A (DNA-directed RNA polymerase II subunit M) (Glutamate receptor-like protein 1A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 8 ( ENSG00000255529 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P0CAP2 |
| Gene Card | POLR2M |
| Uniprot ID | P0CAP2 |
| Pfam | PF15328 |
| In ASD | no |
| Allosteric Prediction | no (-1.45360773) |
| Ortholog in Animals | GuineaPig_ POLR2M ( ortholog_one2one ) Mouse_ Polr2m ( ortholog_one2one ) Pig_ POLR2M ( ortholog_one2one ) Rat_ AABR07043557.1 ( ortholog_one2many ) Rabbit_ POLR2M ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MYZAP, CCDC68, TUFT1 |
| Tissue | substantia.nigra |
| Tissue Specificity | Detected in adult an fetal brain. Detected in heart, kidney, skeletal muscle, small intestine, lung, prostate and testis. {ECO:0000269|PubMed:15233991}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001360(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6DRD (EM 3.90A ) |
| DBSNP | NA |
| Subcellular location [CC] | [Isoform 1]: Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
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