| Gene Information | |
|---|---|
| Gene Name | PTPRG |
| Organism | Homo sapiens (Human) |
| Gene Length | 1445 |
| Protein Names | Receptor-type tyrosine-protein phosphatase gamma (Protein-tyrosine phosphatase gamma) (R-PTP-gamma) (EC 3.1.3.48) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000144724 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P23470 |
| Gene Card | PTPRG |
| Uniprot ID | P23470 |
| Pfam | PF00194; PF00041; PF00102 |
| In ASD | no |
| Allosteric Prediction | no (-0.40783991) |
| Ortholog in Animals | Alpaca_ PTPRG ( ortholog_one2one ) Dog_ PTPRG ( ortholog_one2one ) GuineaPig_ PTPRG ( ortholog_one2one ) Macaque_ PTPRG ( ortholog_one2one ) Mouse_ PTPRG ( ortholog_one2one ) Pig_ PTPRG ( ortholog_one2one ) Rat_ Ptprg ( ortholog_one2one ) Rabbit_ PTPRG ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PTPN12, PTPRC, PTPN6, PTPN18, PTPN7, PTPN1, PTPN13, PTPRF, PTPRK, PTPRB, PTPRA, PTPN22, PTPRR, PTPN5, PTPN23, PTPRZ1, PTPN9, PTPRE, PTPN4, PTPRT, PTPRS, PTPRD, PTPN2, PTPRO, PTPRJ, PTPRM, PTPN11, PTPN20, PTPRU, PTPN14, PTPN3, PTPRN, PTPRN2, PTPRH, PTPN21 |
| Tissue | NA |
| Tissue Specificity | Found in a variety of tissues. |
| Pharmacological Animal Models | 0.030291(Chimpanzee);NULL(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2H4V (X-ray 1.55A ) 2HY3 (X-ray 2.60A ) 2NLK (X-ray 2.40A ) 2PBN (X-ray 1.70A ) 3JXH (X-ray 1.70A ) 3QCB (X-ray 2.10A ) 3QCC (X-ray 2.10A ) 3QCD (X-ray 1.80A ) 3QCE (X-ray 2.10A ) 3QCF (X-ray 2.50A ) 3QCG (X-ray 2.05A ) 3QCH (X-ray 2.40A ) 3QCI (X-ray 2.27A ) 3QCJ (X-ray 2.26A ) 3QCK (X-ray 2.05A ) 3QCL (X-ray 2.40A ) 3QCM (X-ray 2.40A ) 3QCN (X-ray 2.41A ) 5E5R (X-ray 2.60A ) |
| DBSNP | rs62620047 rs2292245 rs9870460 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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