| Gene Information | |
|---|---|
| Gene Name | ACTC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 377 |
| Protein Names | Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000159251 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P68032 |
| Gene Card | ACTC1 |
| Uniprot ID | P68032 |
| Pfam | PF00022 |
| In ASD | yes |
| Allosteric Prediction | yes (0.216838928) |
| Ortholog in Animals | Alpaca_ ACTC1 ( ortholog_one2one ) Dog_ ACTC1 ( ortholog_one2one ) GuineaPig_ ACTC1 ( ortholog_one2one ) Macaque_ ACTC1 ( ortholog_one2one ) Mouse_ Actc1 ( ortholog_one2one ) Pig_ ACTC1 ( ortholog_one2one ) Rat_ Actc1 ( ortholog_one2one ) Rabbit_ ACTC1 ( ortholog_one2one ) |
| Ohnologs | ACTA2, ACTA1, ACTG2 |
| Paralogs | ACTBL2, ACTR1A, ACTB, ACTG1, ACTR5, ACTL9, ACTR3, ACTL7A, ACTL7B, ACTL8, ACTA1, ACTL6B, ACTR3B, ACTR3C, ACTRT2, ACTR8, ACTR1B, ACTL6A, ACTR2, ACTR6, ACTRT1, ACTRT3, ACTL10, ACTG2, ACTA2, ACTR10 |
| Tissue | heart, left.atrium, left.ventricle, mitral.valve, atrium |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.034286(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs121912676 rs759495229 rs193922680 rs121912677 rs267606628 rs121912675 rs121912673 rs267606629 rs121912674 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton. |
| Mouse PG classification | HPG |
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