| Gene Information | |
|---|---|
| Gene Name | IRF9 |
| Organism | Homo sapiens (Human) |
| Gene Length | 393 |
| Protein Names | Interferon regulatory factor 9 (IRF-9) (IFN-alpha-responsive transcription factor subunit) (ISGF3 p48 subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF-3 gamma) (Transcriptional regulator ISGF3 subunit gamma) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 168 ( ENSG00000213928 ) 3 ( ENSG00000285048 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q00978 |
| Gene Card | IRF9 |
| Uniprot ID | Q00978 |
| Pfam | PF00605; PF10401 |
| In ASD | no |
| Allosteric Prediction | no (-0.500828639) |
| Ortholog in Animals | Alpaca_ IRF9 ( ortholog_one2one ) GuineaPig_ IRF9 ( ortholog_one2one ) Macaque_ IRF9 ( ortholog_one2one ) Mouse_ Irf9 ( ortholog_one2one ) Pig_ IRF9 ( ortholog_one2one ) Rat_ Irf9 ( ortholog_one2one ) |
| Ohnologs | IRF8, IRF6, IRF4 |
| Paralogs | IRF4, IRF7, IRF5, IRF3, IRF6, IRF2, IRF8, IRF1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs145480303 rs1452927917 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:11846981}. Nucleus {ECO:0000269|PubMed:11846981, ECO:0000269|PubMed:30143481}. Note=Translocated into the nucleus upon activation by IFN-alpha/beta. |
| Mouse PG classification | NA |
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