| Gene Information | |
|---|---|
| Gene Name | PRXL2A |
| Organism | Homo sapiens (Human) |
| Gene Length | 229 |
| Protein Names | Peroxiredoxin-like 2A (Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes) (Protein PAMM) (Redox-regulatory protein FAM213A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000122378 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9BRX8 |
| Gene Card | PRXL2A |
| Uniprot ID | Q9BRX8 |
| Pfam | PF13911 |
| In ASD | no |
| Allosteric Prediction | no (-0.957971084) |
| Ortholog in Animals | Alpaca_ PRXL2A ( ortholog_one2one ) GuineaPig_ PRXL2A ( ortholog_one2one ) Macaque_ PRXL2A ( ortholog_one2one ) Mouse_ Prxl2a ( ortholog_one2one ) Pig_ PRXL2A ( ortholog_one2one ) Rat_ Prxl2a ( ortholog_one2one ) Rabbit_ PRXL2A ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in CSF1 and TNFSF11-stimulated CD14(+) peripheral blood mononuclear cells (PBMCs). {ECO:0000269|PubMed:19951071}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:19951071}. Secreted {ECO:0000269|PubMed:26438880}. Note=Secreted from mature adipocytes but not from preadipocytes. {ECO:0000269|PubMed:26438880}. |
| Mouse PG classification | NA |
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