Gene Information
Gene NamePTPCAAX2
OrganismHomo sapiens (Human)
Gene Length167
Protein NamesProtein tyrosine phosphatase type IVA 2 (EC 3.1.3.48) (HU-PP-1) (OV-1) (PTP(CAAXII)) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ12974
Gene CardPTP4A2
Uniprot IDQ12974
PfamPF00102
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityUbiquitously expressed, with highest levels in skeletal muscle, heart and thymus. Overexpressed in prostate tumor tissue. {ECO:0000269|PubMed:10940933, ECO:0000269|PubMed:11734337, ECO:0000269|PubMed:8661118}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 5K22  (X-ray  3.00A  5K23  (X-ray  2.96A  5K25  (X-ray  3.05A  6WUR  (X-ray  2.88A 
DBSNP NA 
Subcellular location [CC]Cell membrane. Early endosome. Cytoplasm.
Mouse PG classificationNA
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