| Gene Information | |
|---|---|
| Gene Name | NSUN5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 429 |
| Protein Names | 28S rRNA (cytosine-C(5))-methyltransferase (EC 2.1.1.-) (NOL1-related protein) (NOL1R) (NOL1/NOP2/Sun domain family member 5) (Williams-Beuren syndrome chromosomal region 20A protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000130305 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q96P11 |
| Gene Card | NSUN5 |
| Uniprot ID | Q96P11 |
| Pfam | PF01189 |
| In ASD | no |
| Allosteric Prediction | no (-1.454998352) |
| Ortholog in Animals | Alpaca_ NSUN5 ( ortholog_one2one ) Dog_ NSUN5 ( ortholog_one2one ) GuineaPig_ NSUN5 ( ortholog_one2one ) Macaque_ NSUN5 ( ortholog_one2one ) Mouse_ Nsun5 ( ortholog_one2one ) Pig_ NSUN5 ( ortholog_one2one ) Rat_ Nsun5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NOP2, NSUN6 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous (PubMed:11978965, PubMed:12073013). Detected in placenta, heart and skeletal muscle (PubMed:11978965, PubMed:12073013). {ECO:0000269|PubMed:11978965, ECO:0000269|PubMed:12073013}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2B9E (X-ray 1.65A ) |
| DBSNP | rs34913552 |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000269|PubMed:31722427}. |
| Mouse PG classification | NA |
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