| Gene Information | |
|---|---|
| Gene Name | RNASE9 |
| Organism | Homo sapiens (Human) |
| Gene Length | 205 |
| Protein Names | Inactive ribonuclease-like protein 9 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000188655 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P60153 |
| Gene Card | RNASE9 |
| Uniprot ID | P60153 |
| Pfam | PF00074 |
| In ASD | no |
| Allosteric Prediction | no (-1.445129342) |
| Ortholog in Animals | Alpaca_ RNASE9 ( ortholog_one2one ) Dog_ RNASE9 ( ortholog_one2one ) Mouse_ Rnase9 ( ortholog_one2one ) Rat_ Rnase9 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RNASE10, RNASE6, RNASE2, RNASE3, RNASE1, RNASE11, ANG, RNASE4, RNASE12, RNASE13, RNASE8, RNASE7 |
| Tissue | epididymis |
| Tissue Specificity | At the mRNA level, widely expressed (PubMed:18992174). At protein level, restricted to epididymis (PubMed:19137000). Expressed in spermatozoa (sperm head and neck), with higher levels on ejaculated and epididymal sperm than on testicular sperm (at protein level). Expressed in the epithelial cells of the epididymal tubule (at protein level). Not detected in muscle. {ECO:0000269|PubMed:18992174, ECO:0000269|PubMed:19137000}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12590446 rs1243647 |
| Subcellular location [CC] | Secreted {ECO:0000305}. |
| Mouse PG classification | NA |
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