Gene Information | |
---|---|
Gene Name | PTOV2 |
Organism | Homo sapiens (Human) |
Gene Length | 747 |
Protein Names | Mediator of RNA polymerase II transcription subunit 25 (Activator interaction domain-containing protein 1) (Activator-recruited cofactor 92 kDa component) (ARC92) (Mediator complex subunit 25) (p78) |
Target Name | NA |
Target Type | NA |
Gene Age | NA |
Evolutionary Stage | NA |
AlphaFoldDB | Q71SY5 |
Gene Card | MED25 |
Uniprot ID | Q71SY5 |
Pfam | PF11232; PF11244; PF11235; PF11265 |
In ASD | yes |
Allosteric Prediction | NA |
Ortholog in Animals | NA |
Ohnologs | NA |
Paralogs | NA |
Tissue | NA |
Tissue Specificity | Ubiquitously expressed. Highest levels in brain, heart, kidney, peripheral leukocytes, placenta, skeletal muscle and spleen. {ECO:0000269|PubMed:14657022, ECO:0000269|PubMed:14983011}. |
Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.024(Rabbit) |
Gene Ontology (biological process) |
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Gene Ontology (cellular component) |
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Gene Ontology (molecular function) |
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PDB | 2KY6 (NMR - ) 2L23 (NMR - ) 2L6U (NMR - ) 2XNF (NMR - ) 7EMF (EM 3.50A ) 7LBM (EM 4.80A ) |
DBSNP | rs794729668 rs781140315 rs145770066 |
Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:14657022}. |
Mouse PG classification | NA |
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