Gene Information
Gene NamePTOV2
OrganismHomo sapiens (Human)
Gene Length747
Protein NamesMediator of RNA polymerase II transcription subunit 25 (Activator interaction domain-containing protein 1) (Activator-recruited cofactor 92 kDa component) (ARC92) (Mediator complex subunit 25) (p78)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ71SY5
Gene CardMED25
Uniprot IDQ71SY5
PfamPF11232; PF11244; PF11235; PF11265
In ASDyes
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityUbiquitously expressed. Highest levels in brain, heart, kidney, peripheral leukocytes, placenta, skeletal muscle and spleen. {ECO:0000269|PubMed:14657022, ECO:0000269|PubMed:14983011}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.024(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2KY6  (NMR  2L23  (NMR  2L6U  (NMR  2XNF  (NMR  7EMF  (EM  3.50A  7LBM  (EM  4.80A 
DBSNP rs794729668  rs781140315  rs145770066 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:14657022}.
Mouse PG classificationNA
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