| Gene Information | |
|---|---|
| Gene Name | PTOV1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 416 |
| Protein Names | Prostate tumor-overexpressed gene 1 protein (PTOV-1) (Activator interaction domain-containing protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 132 ( ENSG00000104960 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q86YD1 |
| Gene Card | PTOV1 |
| Uniprot ID | Q86YD1 |
| Pfam | PF11232 |
| In ASD | no |
| Allosteric Prediction | no (-0.72732554) |
| Ortholog in Animals | Alpaca_ PTOV1 ( ortholog_one2one ) Dog_ PTOV1 ( ortholog_one2one ) GuineaPig_ PTOV1 ( ortholog_one2one ) Macaque_ PTOV1 ( ortholog_one2one ) Mouse_ Ptov1 ( ortholog_one2one ) Pig_ PTOV1 ( ortholog_one2one ) Rat_ Ptov1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MED25 |
| Tissue | NA |
| Tissue Specificity | Expressed in brain, heart, kidney, liver, placenta, skeletal muscle and small intestine. {ECO:0000269|PubMed:11313889}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:12598323, ECO:0000269|PubMed:16639697}. Nucleus {ECO:0000269|PubMed:12598323, ECO:0000269|PubMed:15713644}. Cell membrane {ECO:0000269|PubMed:15713644}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:11313889}. Note=Translocates from the cytoplasm to the nucleus at the onset of S-phase (PubMed:12598323). Also localizes to lipid rafts (PubMed:15713644). {ECO:0000269|PubMed:12598323, ECO:0000269|PubMed:15713644}. |
| Mouse PG classification | NA |
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