| Gene Information | |
|---|---|
| Gene Name | PHF3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 2039 |
| Protein Names | PHD finger protein 3 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000118482 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q92576 |
| Gene Card | PHF3 |
| Uniprot ID | Q92576 |
| Pfam | PF00628; PF07744; PF07500 |
| In ASD | no |
| Allosteric Prediction | no (-1.133150325) |
| Ortholog in Animals | Alpaca_ PHF3 ( ortholog_one2one ) Dog_ PHF3 ( ortholog_one2one ) Macaque_ PHF3 ( ortholog_one2one ) Mouse_ Phf3 ( ortholog_one2one ) Pig_ PHF3 ( ortholog_one2one ) Rat_ Phf3 ( ortholog_one2one ) Rabbit_ PHF3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SPOCD1, DIDO1 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Expression is significantly reduced or lost in glioblastomas, glioblastoma cell lines, anaplastic astrocytomas, and astrocytomas. {ECO:0000269|PubMed:11856869}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2DME (NMR - ) 6IC8 (X-ray 1.93A ) 6IC9 (X-ray 1.75A ) 6Q2V (X-ray 2.59A ) 6Q5Y (X-ray 2.85A ) |
| DBSNP | rs34288820 rs3734881 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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