| Gene Information | |
|---|---|
| Gene Name | PTGR3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 377 |
| Protein Names | Prostaglandin reductase 3 (PRG-3) (EC 1.3.1.48) (Zinc-binding alcohol dehydrogenase domain-containing protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000180011 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8N4Q0 |
| Gene Card | ZADH2 |
| Uniprot ID | Q8N4Q0 |
| Pfam | PF08240; PF00107 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | Alpaca_ PTGR3 ( ortholog_one2one ) Dog_ ZADH2 ( ortholog_one2one ) GuineaPig_ PTGR3 ( ortholog_one2one ) Macaque_ PTGR3 ( ortholog_one2one ) Mouse_ Zadh2 ( ortholog_one2one ) Pig_ PTGR3 ( ortholog_one2one ) Rat_ Zadh2 ( ortholog_one2one ) Rabbit_ PTGR3 ( ortholog_one2one ) |
| Ohnologs | VAT1L |
| Paralogs | MECR, CRYZ, RTN4IP1, PTGR2, TP53I3, CRYZL1, ADH6, ADH4, SORD, ADH1B, ADH1A, ADH1C, VAT1L, PTGR1, ADH5, ADH7, VAT1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2C0C (X-ray 1.45A ) 2WEK (X-ray 1.90A ) 2X1H (X-ray 1.75A ) 2X7H (X-ray 1.60A ) 7ZEJ (X-ray 1.79A ) |
| DBSNP | rs17056661 |
| Subcellular location [CC] | Peroxisome {ECO:0000250|UniProtKB:Q8BGC4}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |