| Gene Information | |
|---|---|
| Gene Name | PTGR2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 351 |
| Protein Names | Prostaglandin reductase 2 (PRG-2) (EC 1.3.1.48) (15-oxoprostaglandin 13-reductase) (Zinc-binding alcohol dehydrogenase domain-containing protein 1) |
| Target Name | prostaglandin reductase 2 |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000140043 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q8N8N7 |
| Gene Card | PTGR2 |
| Uniprot ID | Q8N8N7 |
| Pfam | PF16884; PF00107 |
| In ASD | no |
| Allosteric Prediction | no (-0.12542347) |
| Ortholog in Animals | Alpaca_ PTGR2 ( ortholog_one2one ) Dog_ PTGR2 ( ortholog_one2one ) GuineaPig_ PTGR2 ( ortholog_one2one ) Macaque_ PTGR2 ( ortholog_one2one ) Mouse_ Ptgr2 ( ortholog_one2one ) Pig_ PTGR2 ( ortholog_one2one ) Rat_ Ptgr2 ( ortholog_one2one ) Rabbit_ PTGR2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MECR, CRYZ, RTN4IP1, TP53I3, CRYZL1, PTGR3, ADH6, ADH4, SORD, ADH1B, ADH1A, ADH1C, VAT1L, PTGR1, ADH5, ADH7, VAT1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:15004468}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2VNA (X-ray 2.17A ) 2W4Q (X-ray 2.00A ) 2W98 (X-ray 1.85A ) 2ZB4 (X-ray 1.63A ) 2ZB7 (X-ray 1.80A ) 2ZB8 (X-ray 2.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. |
| Mouse PG classification | NA |
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