| Gene Information | |
|---|---|
| Gene Name | ALDH8A1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 487 |
| Protein Names | 2-aminomuconic semialdehyde dehydrogenase (EC 1.2.1.32) (Aldehyde dehydrogenase 12) (Aldehyde dehydrogenase family 8 member A1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000118514 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9H2A2 |
| Gene Card | ALDH8A1 |
| Uniprot ID | Q9H2A2 |
| Pfam | PF00171 |
| In ASD | no |
| Allosteric Prediction | no (-0.401805853) |
| Ortholog in Animals | Alpaca_ ALDH8A1 ( ortholog_one2one ) Dog_ ALDH8A1 ( ortholog_one2one ) GuineaPig_ ALDH8A1 ( ortholog_one2one ) Mouse_ Aldh8a1 ( ortholog_one2one ) Pig_ ALDH8A1 ( ortholog_one2one ) Rat_ Aldh8a1 ( ortholog_one2one ) Rabbit_ ALDH8A1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ALDH7A1, ALDH1B1, ALDH3A2, ALDH1A1, ALDH3B1, ALDH3B2, ALDH3A1, ALDH2, ALDH9A1, ALDH1A2, ALDH6A1, ALDH5A1, ALDH1L1, ALDH1A3, ALDH1L2, ALDH4A1, ALDH16A1 |
| Tissue | kidney, liver |
| Tissue Specificity | Highly expressed in adult kidney and liver. Detected at lower levels in fetal liver and kidney. {ECO:0000269|PubMed:11007799}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);NULL(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2294315 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |