| Gene Information | |
|---|---|
| Gene Name | NEIL2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 332 |
| Protein Names | Endonuclease 8-like 2 (EC 3.2.2.-) (EC 4.2.99.18) (DNA glycosylase/AP lyase Neil2) (DNA-(apurinic or apyrimidinic site) lyase Neil2) (Endonuclease VIII-like 2) (Nei homolog 2) (NEH2) (Nei-like protein 2) |
| Target Name | endonuclease 8-like 2 |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000154328 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q969S2 |
| Gene Card | NEIL2 |
| Uniprot ID | Q969S2 |
| Pfam | PF06831 |
| In ASD | no |
| Allosteric Prediction | no (-0.535089047) |
| Ortholog in Animals | Alpaca_ NEIL2 ( ortholog_one2one ) Dog_ NEIL2 ( ortholog_one2one ) GuineaPig_ NEIL2 ( ortholog_one2one ) Macaque_ NEIL2 ( ortholog_one2one ) Mouse_ Neil2 ( ortholog_one2one ) Pig_ NEIL2 ( ortholog_one2one ) Rat_ Neil2 ( ortholog_one2one ) Rabbit_ NEIL2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NEIL3, NEIL1 |
| Tissue | NA |
| Tissue Specificity | Detected in testis, skeletal muscle, heart, brain, placenta, lung, pancreas, kidney and liver. {ECO:0000269|PubMed:12097317}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs8191611 rs8191613 rs8191612 rs8191664 rs8191666 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:12097317}. |
| Mouse PG classification | NA |
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