| Gene Information | |
|---|---|
| Gene Name | PTB |
| Organism | Homo sapiens (Human) |
| Gene Length | 531 |
| Protein Names | Polypyrimidine tract-binding protein 2 (Neural polypyrimidine tract-binding protein) (Neurally-enriched homolog of PTB) (PTB-like protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9UKA9 |
| Gene Card | PTBP2 |
| Uniprot ID | Q9UKA9 |
| Pfam | PF00076; PF11835 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Mainly expressed in brain although also detected in other tissues like heart and skeletal muscle. Isoform 1 and isoform 2 are specifically expressed in neuronal tissues. Isoform 3 and isoform 4 are expressed in non-neuronal tissues. Isoform 5 and isoform 6 are truncated forms expressed in non-neuronal tissues. {ECO:0000269|PubMed:11003644, ECO:0000269|PubMed:12213192}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2CQ1 (NMR - ) 2MJU (NMR - ) 4CQ1 (X-ray 1.69A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000250|UniProtKB:Q91Z31}. |
| Mouse PG classification | NA |
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