| Gene Information | |
|---|---|
| Gene Name | XPO5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1204 |
| Protein Names | Exportin-5 (Exp5) (Ran-binding protein 21) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000124571 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9HAV4 |
| Gene Card | XPO5 |
| Uniprot ID | Q9HAV4 |
| Pfam | PF19273; PF08389 |
| In ASD | no |
| Allosteric Prediction | no (-0.296046873) |
| Ortholog in Animals | Alpaca_ XPO5 ( ortholog_one2one ) Dog_ XPO5 ( ortholog_one2one ) GuineaPig_ XPO5 ( ortholog_one2one ) Macaque_ XPO5 ( ortholog_one2one ) Mouse_ Xpo5 ( ortholog_one2one ) Pig_ XPO5 ( ortholog_one2one ) Rat_ Xpo5 ( ortholog_one2one ) Rabbit_ XPO5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | XPO1 |
| Tissue | NA |
| Tissue Specificity | Expressed in heart, brain, placenta, lung, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:11777942}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3A6P (X-ray 2.92A ) 5YU6 (X-ray 3.00A ) 5YU7 (X-ray 3.30A ) |
| DBSNP | rs34324334 rs11544379 rs12173786 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11777942}. Cytoplasm {ECO:0000269|PubMed:11777942}. Note=Shuttles between the nucleus and the cytoplasm. |
| Mouse PG classification | NA |
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