| Gene Information | |
|---|---|
| Gene Name | NPBWR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 328 |
| Protein Names | Neuropeptides B/W receptor type 1 (G-protein coupled receptor 7) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P48145 |
| Gene Card | NPBWR1 |
| Uniprot ID | P48145 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (0.73776254) |
| Ortholog in Animals | Alpaca_ NPBWR1 ( ortholog_one2one ) Dog_ NPBWR1 ( ortholog_one2one ) GuineaPig_ NPBWR1 ( ortholog_one2one ) Macaque_ NPBWR1 ( ortholog_one2one ) Mouse_ Npbwr1 ( ortholog_one2one ) Pig_ NPBWR1 ( ortholog_one2one ) Rat_ Npbwr1 ( ortholog_one2one ) Rabbit_ NPBWR1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SSTR5, SSTR4, OPRL1, GPR149, OPRM1, OPRK1, PTGDR2, SSTR3, CMKLR2, SSTR1, LTB4R, LTB4R2, KISS1R, UTS2R, NPBWR2, SSTR2, OPRD1 |
| Tissue | NA |
| Tissue Specificity | Found in cerebellum and frontal cortex. Detected at high levels in hippocampus, amygdala and trachea; at moderate levels in fetal brain, pituitary gland and prostate. Not in caudate, accumbens, kidney or liver. Also detected at high levels in lung carcinoma. {ECO:0000269|PubMed:12401809}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs772418985 rs33977775 rs36068168 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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