| Gene Information | |
|---|---|
| Gene Name | SPCA2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 946 |
| Protein Names | Calcium-transporting ATPase type 2C member 2 (ATPase 2C2) (EC 7.2.2.10) (Ca(2+)/Mn(2+)-ATPase 2C2) (Secretory pathway Ca(2+)-transporting ATPase type 2) (SPCA2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O75185 |
| Gene Card | ATP2C2 |
| Uniprot ID | O75185 |
| Pfam | PF00689; PF00690 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in the gastrointestinal and respiratory tracts, prostate, thyroid, salivary, and mammary glands (PubMed:15831496). Expressed in colon epithelial cells (at protein level). Expressed in brain and testis (at protein level) (PubMed:15677451). {ECO:0000269|PubMed:15677451, ECO:0000269|PubMed:15831496}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs247818 rs2303853 rs247897 rs62640926 rs16973859 |
| Subcellular location [CC] | Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:15831496}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000269|PubMed:20887894}; Multi-pass membrane protein {ECO:0000255}. Basolateral cell membrane {ECO:0000250|UniProtKB:A7L9Z8}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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