Gene Information
Gene NamePSME3
OrganismHomo sapiens (Human)
Gene Length254
Protein NamesProteasome activator complex subunit 3 (11S regulator complex subunit gamma) (REG-gamma) (Activator of multicatalytic protease subunit 3) (Ki nuclear autoantigen) (Proteasome activator 28 subunit gamma) (PA28g) (PA28gamma)
Target NameNA
Target TypeNA
Gene Age1064 ( ENSG00000131467 )
Evolutionary StageEukaryota
AlphaFoldDBP61289
Gene CardPSME3
Uniprot IDP61289
PfamPF02251; PF02252
In ASDno
Allosteric Predictionno (-0.37829002)
Ortholog in AnimalsAlpaca_ PSME3 ( ortholog_one2many )
Dog_ PSME3 ( ortholog_one2one )
GuineaPig_ PSME3 ( ortholog_one2one )
Macaque_ PSME3 ( ortholog_one2one )
Mouse_ Psme3 ( ortholog_one2one )
Pig_ PSME3 ( ortholog_one2one )
Rat_ AABR07062753.1 ( ortholog_one2one )
Rabbit_ PSME3 ( ortholog_one2one )
OhnologsNA
ParalogsPSME1, PSME2
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:10657252, ECO:0000269|PubMed:12629132}. Cytoplasm {ECO:0000250}. Note=Localizes to the cytoplasm during mitosis following nuclear envelope breakdown at this distinct stage of the cell cycle which allows its interaction with MAP3K3 kinase. {ECO:0000250}.
Mouse PG classificationNA
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