| Gene Information | |
|---|---|
| Gene Name | ECE2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 811 |
| Protein Names | Endothelin-converting enzyme 2 (ECE-2) (EC 3.4.24.71) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 18 ( ENSG00000145194 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P0DPD6 |
| Gene Card | ECE2 |
| Uniprot ID | P0DPD6 |
| Pfam | PF01431; PF05649 |
| In ASD | no |
| Allosteric Prediction | no (-0.383929766) |
| Ortholog in Animals | Alpaca_ ECE2 ( ortholog_one2one ) Dog_ ECE2 ( ortholog_one2one ) GuineaPig_ ECE2 ( ortholog_one2one ) Macaque_ ECE2 ( ortholog_one2one ) Mouse_ Ece2 ( ortholog_one2one ) Pig_ ECE2 ( ortholog_one2one ) Rat_ Ece2 ( ortholog_one2one ) Rabbit_ ECE2 ( ortholog_one2one ) |
| Ohnologs | ECE1, ECEL1 |
| Paralogs | KEL, MMEL1, PHEX, ECE1, MME, ECEL1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35875049 |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000250|UniProtKB:F1N476}; Single-pass type II membrane protein {ECO:0000305}. Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250|UniProtKB:F1N476}. |
| Mouse PG classification | NA |
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