| Gene Information | |
|---|---|
| Gene Name | HABP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 560 |
| Protein Names | Hyaluronan-binding protein 2 (EC 3.4.21.-) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) (Hepatocyte growth factor activator-like protein) (Plasma hyaluronan-binding protein) [Cleaved into: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form] |
| Target Name | hyaluronan-binding protein 2 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000148702 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q14520 |
| Gene Card | HABP2 |
| Uniprot ID | Q14520 |
| Pfam | PF00008; PF00051; PF00089 |
| In ASD | no |
| Allosteric Prediction | no (-0.063568067) |
| Ortholog in Animals | Alpaca_ HABP2 ( ortholog_one2one ) Dog_ HABP2 ( ortholog_one2one ) GuineaPig_ HABP2 ( ortholog_one2one ) Macaque_ HABP2 ( ortholog_one2one ) Mouse_ Habp2 ( ortholog_one2one ) Pig_ HABP2 ( ortholog_one2one ) Rat_ Habp2 ( ortholog_one2one ) Rabbit_ HABP2 ( ortholog_one2one ) |
| Ohnologs | PLAT, HGFAC, PLAU, F12 |
| Paralogs | GZMA, MST1, PIK3IP1, GZMK, HGF |
| Tissue | liver |
| Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:8827452}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);NULL(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs11575750 rs11575688 rs7080536 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:8827452}. Note=Secreted as an inactive single-chain precursor and is then activated to a heterodimeric form. |
| Mouse PG classification | LPG |
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