| Gene Information | |
|---|---|
| Gene Name | PSMB10 |
| Organism | Homo sapiens (Human) |
| Gene Length | 273 |
| Protein Names | Proteasome subunit beta type-10 (EC 3.4.25.1) (Low molecular mass protein 10) (Macropain subunit MECl-1) (Multicatalytic endopeptidase complex subunit MECl-1) (Proteasome MECl-1) (Proteasome subunit beta-2i) |
| Target Name | proteasome subunit beta type-10 |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000205220 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P40306 |
| Gene Card | PSMB10 |
| Uniprot ID | P40306 |
| Pfam | PF12465; PF00227 |
| In ASD | no |
| Allosteric Prediction | no (-0.340108569) |
| Ortholog in Animals | Alpaca_ PSMB10 ( ortholog_one2one ) Dog_ PSMB10 ( ortholog_one2one ) GuineaPig_ PSMB10 ( ortholog_one2one ) Macaque_ PSMB10 ( ortholog_one2one ) Mouse_ Psmb10 ( ortholog_one2one ) Pig_ PSMB10 ( ortholog_one2one ) Rat_ Psmb10 ( ortholog_one2one ) Rabbit_ PSMB10 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PSMB11, PSMA7, PSMA6, PSMA3, PSMB5, PSMA4, PSMB4, PSMB6, PSMA8, PSMA5, PSMA2, PSMB2, PSMB7, PSMB1, PSMA1, PSMB9, PSMB8, PSMB3 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.245608(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6AVO (EM 3.80A ) 6E5B (X-ray 2.77A ) 6HV3 (X-ray 2.70A ) 6HV4 (X-ray 3.00A ) 6HV5 (X-ray 3.00A ) 6HV7 (X-ray 3.40A ) 6HVA (X-ray 2.90A ) 6HVR (X-ray 2.70A ) 6HVS (X-ray 3.10A ) 6HVT (X-ray 2.90A ) 6HVU (X-ray 2.90A ) 6HVV (X-ray 2.70A ) 6HVW (X-ray 3.00A ) 7AWE (X-ray 2.29A ) 7B12 (X-ray 2.43A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000255|PROSITE-ProRule:PRU00809}. Nucleus {ECO:0000250}. |
| Mouse PG classification | NA |
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