| Gene Information | |
|---|---|
| Gene Name | SPSB2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 263 |
| Protein Names | SPRY domain-containing SOCS box protein 2 (SSB-2) (Gene-rich cluster protein C9) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 168 ( ENSG00000111671 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q99619 |
| Gene Card | SPSB2 |
| Uniprot ID | Q99619 |
| Pfam | PF07525; PF00622 |
| In ASD | no |
| Allosteric Prediction | no (-0.217732164) |
| Ortholog in Animals | Alpaca_ SPSB2 ( ortholog_one2one ) Dog_ SPSB2 ( ortholog_one2one ) GuineaPig_ SPSB2 ( ortholog_one2one ) Macaque_ SPSB2 ( ortholog_one2one ) Mouse_ Spsb2 ( ortholog_one2one ) Pig_ SPSB2 ( ortholog_one2one ) Rat_ Spsb2 ( ortholog_one2one ) Rabbit_ SPSB2 ( ortholog_one2one ) |
| Ohnologs | SPSB1, SPSB4 |
| Paralogs | SPSB4, SPSB1, FBXO45, SPSB3 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.022222(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3EMW (X-ray 1.80A ) 5XN3 (X-ray 1.34A ) 6DN5 (X-ray 2.40A ) 6DN6 (X-ray 1.59A ) 6JKJ (X-ray 1.90A ) 6JWM (X-ray 1.23A ) 6JWN (X-ray 1.61A ) 6KEY (X-ray 1.24A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000305}. Cytoplasm, cytosol {ECO:0000269|PubMed:21199876}. Note=Exhibits a diffuse cytosolic localization. {ECO:0000269|PubMed:21199876}. |
| Mouse PG classification | NA |
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