Gene Information
Gene NameCPLX3
OrganismHomo sapiens (Human)
Gene Length158
Protein NamesComplexin-3 (Complexin III) (CPX III)
Target NameNA
Target TypeNA
Gene Age810 ( ENSG00000213578 )
Evolutionary StageVertebrata
AlphaFoldDBQ8WVH0
Gene CardCPLX3
Uniprot IDQ8WVH0
PfamPF05835
In ASDno
Allosteric Predictionno (-0.702099864)
Ortholog in AnimalsAlpaca_ CPLX3 ( ortholog_one2one )
Dog_ CPLX3 ( ortholog_one2one )
GuineaPig_ CPLX3 ( ortholog_one2one )
Macaque_ CPLX3 ( ortholog_one2one )
Mouse_ Cplx3 ( ortholog_one2one )
Pig_ CPLX3 ( ortholog_one2one )
Rat_ Cplx3 ( ortholog_one2one )
Rabbit_ CPLX3 ( ortholog_one2one )
OhnologsNA
ParalogsCPLX4, CPLX1, CPLX2
Tissueprostate
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Synapse {ECO:0000250|UniProtKB:Q8R1B5}. Cell membrane;
Lipid-anchor {ECO:0000250|UniProtKB:Q8R1B5}. Note=Enriched at the synaptic terminal (By similarity). Localized at glycinergic synaptic contacts of AII amacrine cells with OFF cone bipolar cells in the OFF sublamina of the retina inner nuclear layer (By similarity). {ECO:0000250|UniProtKB:Q8R1B5}.
Mouse PG classificationNA
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