| Gene Information | |
|---|---|
| Gene Name | DPT |
| Organism | Homo sapiens (Human) |
| Gene Length | 201 |
| Protein Names | Dermatopontin (Tyrosine-rich acidic matrix protein) (TRAMP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000143196 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q07507 |
| Gene Card | DPT |
| Uniprot ID | Q07507 |
| Pfam | PF14704 |
| In ASD | no |
| Allosteric Prediction | no (-1.540922716) |
| Ortholog in Animals | Alpaca_ DPT ( ortholog_one2one ) Dog_ DPT ( ortholog_one2one ) GuineaPig_ DPT ( ortholog_one2one ) Macaque_ DPT ( ortholog_one2one ) Mouse_ Dpt ( ortholog_one2one ) Pig_ DPT ( ortholog_one2one ) Rat_ Dpt ( ortholog_one2one ) Rabbit_ DPT ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in fibroblasts, heart, skeletal muscle, brain and pancreas. Expressed at an intermediate level in lung and kidney, and at a low level in liver and placenta. Expressed at a lower level in fibroblasts from hypertrophic scar lesional skin and in fibroblasts from patients with systemic sclerosis than in normal skin fibroblasts. {ECO:0000269|PubMed:10233760, ECO:0000269|PubMed:8104875}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6698023 |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix {ECO:0000250}. |
| Mouse PG classification | NA |
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