| Gene Information | |
|---|---|
| Gene Name | MOGAT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 335 |
| Protein Names | 2-acylglycerol O-acyltransferase 1 (EC 2.3.1.22) (Acyl-CoA:monoacylglycerol acyltransferase 1) (MGAT1) (Diacylglycerol O-acyltransferase candidate 2) (hDC2) (Diacylglycerol acyltransferase 2-like protein 1) (Monoacylglycerol O-acyltransferase 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000124003 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96PD6 |
| Gene Card | MOGAT1 |
| Uniprot ID | Q96PD6 |
| Pfam | PF03982 |
| In ASD | no |
| Allosteric Prediction | no (-0.805246065) |
| Ortholog in Animals | Alpaca_ MOGAT1 ( ortholog_one2one ) Dog_ MOGAT1 ( ortholog_one2one ) GuineaPig_ MOGAT1 ( ortholog_one2one ) Macaque_ MOGAT1 ( ortholog_one2one ) Mouse_ Mogat1 ( ortholog_one2one ) Pig_ MOGAT1 ( ortholog_one2one ) Rat_ Mogat1 ( ortholog_one2one ) Rabbit_ MOGAT1 ( ortholog_one2one ) |
| Ohnologs | DGAT2, MOGAT3, MOGAT2 |
| Paralogs | MOGAT2, AWAT2, AWAT1, DGAT2L6, MOGAT3, DGAT2 |
| Tissue | gall.bladder |
| Tissue Specificity | Expressed in stomach and liver. {ECO:0000269|PubMed:12621063}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.2(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35959734 rs1868024 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q91ZV4}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q91ZV4}. |
| Mouse PG classification | NA |
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