| Gene Information | |
|---|---|
| Gene Name | GPR55 |
| Organism | Homo sapiens (Human) |
| Gene Length | 319 |
| Protein Names | G-protein coupled receptor 55 |
| Target Name | g-protein coupled receptor 55 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000135898 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9Y2T6 |
| Gene Card | GPR55 |
| Uniprot ID | Q9Y2T6 |
| Pfam | PF00001 |
| In ASD | yes |
| Allosteric Prediction | yes (1.407055591) |
| Ortholog in Animals | Alpaca_ GPR55 ( ortholog_one2one ) Dog_ GPR55 ( ortholog_one2one ) GuineaPig_ GPR55 ( ortholog_one2one ) Macaque_ GPR55 ( ortholog_one2one ) Mouse_ Gpr55 ( ortholog_one2one ) Pig_ GPR55 ( ortholog_one2one ) Rat_ Gpr55 ( ortholog_one2one ) Rabbit_ GPR55 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | F2RL2, P2RY8, F2RL1, F2R, F2RL3, GPR18, GPR65, CYSLTR2, GPR17, GPR4, CYSLTR1, GPR20, GPR35, LPAR4, LPAR6, P2RY10 |
| Tissue | NA |
| Tissue Specificity | Expressed in the caudate nucleus and putamen, but not detected in the hippocampus, thalamus, pons cerebellum, frontal cortex of the brain or in the liver. Expressed in osteoclasts and osteoblasts. {ECO:0000269|PubMed:19805329, ECO:0000269|PubMed:9931487}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3749073 rs34229723 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:18757503}; Multi-pass membrane protein {ECO:0000269|PubMed:18757503}. |
| Mouse PG classification | NA |
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