| Gene Information | |
|---|---|
| Gene Name | PSD2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 771 |
| Protein Names | PH and SEC7 domain-containing protein 2 (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 C) (Exchange factor for ARF6 C) (Pleckstrin homology and SEC7 domain-containing protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000146005 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9BQI7 |
| Gene Card | PSD2 |
| Uniprot ID | Q9BQI7 |
| Pfam | PF15410; PF01369 |
| In ASD | no |
| Allosteric Prediction | no (-0.723992127) |
| Ortholog in Animals | Alpaca_ PSD2 ( ortholog_one2one ) Dog_ PSD2 ( ortholog_one2one ) GuineaPig_ PSD2 ( ortholog_one2one ) Macaque_ PSD2 ( ortholog_one2one ) Mouse_ Psd2 ( ortholog_one2one ) Pig_ PSD2 ( ortholog_one2one ) Rat_ Psd2 ( ortholog_one2one ) Rabbit_ PSD2 ( ortholog_one2one ) |
| Ohnologs | PSD, PSD3, PSD4 |
| Paralogs | PSD3, ARFGEF2, CYTH4, MON2, GBF1, ARFGEF1, PSD, PSD4, FBXO8, CYTH1, IQSEC3, IQSEC1, CYTH2, IQSEC2, CYTH3 |
| Tissue | brain, cerebral.cortex |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34880693 rs3797902 rs35714177 |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:Q6P1I6}; Single-pass membrane protein {ECO:0000305}. Cell projection, ruffle membrane {ECO:0000250|UniProtKB:Q6P1I6}. Cleavage furrow {ECO:0000250|UniProtKB:Q6P1I6}. Note=In interphase associated with the plasma membrane, in particular with membrane ruffling regions. In cells undergoing cytokinesis, transiently found around the ingressing cleavage furrow. Not detected at the midbody ring/Flemming body. {ECO:0000250|UniProtKB:Q6P1I6}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |