| Gene Information | |
|---|---|
| Gene Name | CTDSP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 261 |
| Protein Names | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (EC 3.1.3.16) (Nuclear LIM interactor-interacting factor 3) (NLI-IF) (NLI-interacting factor 3) (Small C-terminal domain phosphatase 1) (SCP1) (Small CTD phosphatase 1) |
| Target Name | carboxy-terminal domain rna polymerase ii polypeptide a small phosphatase 1 |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000144579 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9GZU7 |
| Gene Card | CTDSP1 |
| Uniprot ID | Q9GZU7 |
| Pfam | PF03031 |
| In ASD | no |
| Allosteric Prediction | no (-0.125138932) |
| Ortholog in Animals | Alpaca_ CTDSP1 ( ortholog_one2one ) Dog_ CTDSP1 ( ortholog_one2one ) GuineaPig_ CTDSP1 ( ortholog_one2one ) Mouse_ Ctdsp1 ( ortholog_one2one ) Pig_ CTDSP1 ( ortholog_one2one ) Rat_ Ctdsp1 ( ortholog_one2many ) |
| Ohnologs | CTDSPL, CTDSP2 |
| Paralogs | CTDSP2, CTDSPL, CTDNEP1, CTDSPL2, TIMM50 |
| Tissue | NA |
| Tissue Specificity | Expression is restricted to non-neuronal tissues. Highest expression in skeletal muscle, spleen, lung and placenta. {ECO:0000269|PubMed:15681389}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.004740(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 1T9Z (X-ray 2.30A ) 1TA0 (X-ray 2.10A ) 2GHQ (X-ray 2.05A ) 2GHT (X-ray 1.80A ) 3L0B (X-ray 2.35A ) 3L0C (X-ray 2.45A ) 3L0Y (X-ray 2.30A ) 3PGL (X-ray 2.35A ) 4YGY (X-ray 2.36A ) 4YH1 (X-ray 2.20A ) 6DU3 (X-ray 2.58A ) |
| DBSNP | rs2227249 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:12721286}. Note=Colocalizes with RNA polymerase II. |
| Mouse PG classification | NA |
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