Gene Information
Gene NamePSAT1
OrganismHomo sapiens (Human)
Gene Length370
Protein NamesPhosphoserine aminotransferase (EC 2.6.1.52) (Phosphohydroxythreonine aminotransferase) (PSAT)
Target Namephosphoserine aminotransferase
Target TypeNA
Gene Age1488 ( ENSG00000135069 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ9Y617
Gene CardPSAT1
Uniprot IDQ9Y617
PfamPF00266
In ASDno
Allosteric Predictionyes (0.327878025)
Ortholog in AnimalsAlpaca_ PSAT1 ( ortholog_one2one )
Dog_ PSAT1 ( ortholog_one2one )
GuineaPig_ PSAT1 ( ortholog_one2one )
Mouse_ Psat1 ( ortholog_one2one )
Pig_ PSAT1 ( ortholog_one2one )
Rat_ AABR07011698.1 ( ortholog_one2many )
Rat_ Psat1 ( ortholog_one2many )
Rabbit_ PSAT1 ( ortholog_one2one )
OhnologsNA
ParalogsAGXT
TissueNA
Tissue SpecificityExpressed at high levels in the brain, liver, kidney and pancreas, and very weakly expressed in the thymus, prostate, testis and colon.
Pharmacological Animal Models0.000730(Chimpanzee);NULL(Mouse);NULL(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 3E77  (X-ray  2.50A 
DBSNP rs11540974  rs587777778  rs118203967  rs587777777 
Subcellular location [CC]NA
Mouse PG classificationNA
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