| Gene Information | |
|---|---|
| Gene Name | CDC7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 574 |
| Protein Names | Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) (EC 2.7.11.1) |
| Target Name | cdc7-related kinase |
| Target Type | Clinical trial target |
| Gene Age | 1488 ( ENSG00000097046 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O00311 |
| Gene Card | CDC7 |
| Uniprot ID | O00311 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | yes (0.080036785) |
| Ortholog in Animals | Alpaca_ CDC7 ( ortholog_one2one ) Dog_ CDC7 ( ortholog_one2one ) GuineaPig_ CDC7 ( ortholog_one2one ) Macaque_ CDC7 ( ortholog_one2one ) Mouse_ Cdc7 ( ortholog_one2one ) Pig_ CDC7 ( ortholog_one2one ) Rat_ Cdc7 ( ortholog_one2one ) Rabbit_ CDC7 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CSNK1G3, TTBK2, VRK3, CSNK1A1L, VRK1, CSNK1G1, CSNK1A1, CSNK1G2, CSNK1E, CSNK1D, VRK2, TTBK1 |
| Tissue | pineal.gland, testis |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.004836(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4F99 (X-ray 2.33A ) 4F9A (X-ray 2.17A ) 4F9B (X-ray 2.50A ) 4F9C (X-ray 2.08A ) 5UWQ (X-ray 2.28A ) 5UWR (X-ray 2.24A ) 6YA6 (X-ray 1.44A ) 6YA7 (X-ray 1.67A ) 6YA8 (X-ray 1.79A ) |
| DBSNP | rs13447459 rs13447492 rs13447493 rs13447503 rs34979509 rs56327502 rs13447539 rs56381770 rs35055915 |
| Subcellular location [CC] | Nucleus {ECO:0000305|PubMed:27401717}. |
| Mouse PG classification | NA |
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