Gene Information
Gene NamePSAP
OrganismHomo sapiens (Human)
Gene Length389
Protein NamesMitochondrial carrier homolog 1 (Presenilin-associated protein)
Target Nameproactivator polypeptide
Target TypeNA
Gene Age544 ( ENSG00000197746 )
Evolutionary StageEukaryota
AlphaFoldDBQ9NZJ7
Gene CardMTCH1
Uniprot IDQ9NZJ7
PfamPF00153
In ASDno
Allosteric Predictionyes (1.333198911)
Ortholog in AnimalsAlpaca_ PSAP ( ortholog_one2one )
Dog_ PSAP ( ortholog_one2one )
GuineaPig_ PSAP ( ortholog_one2one )
Macaque_ PSAP ( ortholog_one2one )
Mouse_ Psap ( ortholog_one2one )
Pig_ PSAP ( ortholog_one2one )
Rat_ Psap ( ortholog_one2one )
Rabbit_ PSAP ( ortholog_one2one )
OhnologsNA
ParalogsPSAPL1, SFTPB
TissueNA
Tissue SpecificityWidely expressed with a predominant expression in brain. {ECO:0000269|PubMed:10551805}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.001759(Rat);0.046154(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Mitochondrion outer membrane {ECO:0000305};
Multi-pass membrane protein {ECO:0000305}.
Mouse PG classificationNA
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