| Gene Information | |
|---|---|
| Gene Name | PSAP |
| Organism | Homo sapiens (Human) |
| Gene Length | 248 |
| Protein Names | Pulmonary surfactant-associated protein A1 (PSP-A) (PSPA) (SP-A) (SP-A1) (35 kDa pulmonary surfactant-associated protein) (Alveolar proteinosis protein) (Collectin-4) |
| Target Name | proactivator polypeptide |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000197746 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8IWL2 |
| Gene Card | SFTPA1 |
| Uniprot ID | Q8IWL2 |
| Pfam | PF00059 |
| In ASD | no |
| Allosteric Prediction | yes (1.333198911) |
| Ortholog in Animals | Alpaca_ PSAP ( ortholog_one2one ) Dog_ PSAP ( ortholog_one2one ) GuineaPig_ PSAP ( ortholog_one2one ) Macaque_ PSAP ( ortholog_one2one ) Mouse_ Psap ( ortholog_one2one ) Pig_ PSAP ( ortholog_one2one ) Rat_ Psap ( ortholog_one2one ) Rabbit_ PSAP ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PSAPL1, SFTPB |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs72659389 rs139899873 rs1059047 rs1136450 rs4253527 rs1965708 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:26792177, ECO:0000269|PubMed:32855221}. Secreted, extracellular space, extracellular matrix {ECO:0000305}. Secreted, extracellular space, surface film {ECO:0000305}. |
| Mouse PG classification | NA |
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