Gene Information
Gene NamePRSS53
OrganismHomo sapiens (Human)
Gene Length553
Protein NamesSerine protease 53 (EC 3.4.21.-) (Polyserine protease 3) (Polyserase-3)
Target NameNA
Target TypeNA
Gene Age382 ( ENSG00000151006 )
Evolutionary StageEumetazoa
AlphaFoldDBQ2L4Q9
Gene CardPRSS53
Uniprot IDQ2L4Q9
PfamPF00089
In ASDno
Allosteric Predictionno (-1.042910215)
Ortholog in AnimalsAlpaca_ PRSS53 ( ortholog_one2one )
Dog_ PRSS53 ( ortholog_one2one )
GuineaPig_ PRSS53 ( ortholog_one2one )
Macaque_ PRSS53 ( ortholog_one2one )
Mouse_ Prss53 ( ortholog_one2one )
Pig_ PRSS53 ( ortholog_one2one )
Rat_ Prss53 ( ortholog_one2one )
Rabbit_ PRSS53 ( ortholog_one2one )
OhnologsNA
ParalogsPRSS36
TissueNA
Tissue SpecificityPredominantly detected in testis, liver, heart and ovary, as well as in several tumor cell lines. {ECO:0000269|PubMed:16566820}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Secreted {ECO:0000269|PubMed:16566820}.
Mouse PG classificationNA
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