| Gene Information | |
|---|---|
| Gene Name | PRSS50 |
| Organism | Homo sapiens (Human) |
| Gene Length | 385 |
| Protein Names | Probable threonine protease PRSS50 (EC 3.4.25.-) (Cancer/testis antigen 20) (Serine protease 50) (Testis-specific protease-like protein 50) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 132 ( ENSG00000283706 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9UI38 |
| Gene Card | PRSS50 |
| Uniprot ID | Q9UI38 |
| Pfam | PF00089 |
| In ASD | no |
| Allosteric Prediction | no (-1.073789918) |
| Ortholog in Animals | Alpaca_ PRSS50 ( ortholog_one2one ) Dog_ PRSS50 ( ortholog_one2one ) GuineaPig_ PRSS50 ( ortholog_one2one ) Macaque_ PRSS50 ( ortholog_one2one ) Mouse_ Prss50 ( ortholog_one2one ) Pig_ PRSS50 ( ortholog_one2one ) Rat_ Prss50 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | OVCH1, PLAT, PRSS48, PLGLB1, PLGLB2, PLG, TMPRSS12, GZMM, KLK15, PRSS37, PRSS27, PRSS33, PRSS57, KLK9 |
| Tissue | NA |
| Tissue Specificity | Testis specific. Differentially expressed in some breast cancer tissues. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34788938 rs35866901 |
| Subcellular location [CC] | Endoplasmic reticulum {ECO:0000305|PubMed:17283160}. Note=May also localize to cytoplasmic membranes. |
| Mouse PG classification | NA |
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