| Gene Information | |
|---|---|
| Gene Name | SEPSECS |
| Organism | Homo sapiens (Human) |
| Gene Length | 501 |
| Protein Names | O-phosphoseryl-tRNA(Sec) selenium transferase (EC 2.9.1.2) (Liver-pancreas antigen) (LP) (SLA-p35) (SLA/LP autoantigen) (Selenocysteine synthase) (Sec synthase) (Selenocysteinyl-tRNA(Sec) synthase) (Sep-tRNA:Sec-tRNA synthase) (SepSecS) (Soluble liver antigen) (SLA) (UGA suppressor tRNA-associated protein) (tRNA(Ser/Sec)-associated antigenic protein) |
| Target Name | o-phosphoseryl-trna(sec) selenium transferase |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000109618 ) |
| Evolutionary Stage | Euk_Archaea |
| AlphaFoldDB | Q9HD40 |
| Gene Card | SEPSECS |
| Uniprot ID | Q9HD40 |
| Pfam | PF05889 |
| In ASD | no |
| Allosteric Prediction | no (-0.604330238) |
| Ortholog in Animals | Alpaca_ SEPSECS ( ortholog_one2one ) Dog_ SEPSECS ( ortholog_one2one ) GuineaPig_ SEPSECS ( ortholog_one2one ) Macaque_ SEPSECS ( ortholog_one2one ) Mouse_ Sepsecs ( ortholog_one2one ) Pig_ SEPSECS ( ortholog_one2one ) Rat_ Sepsecs ( ortholog_one2one ) Rabbit_ SEPSECS ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Primarily expressed in liver, pancreas, kidney and lung. Overexpressed in PHA-stimulated T-cells. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3HL2 (X-ray 2.81A ) 4ZDL (X-ray 2.26A ) 4ZDO (X-ray 2.65A ) 4ZDP (X-ray 2.70A ) 7L1T (X-ray 2.25A ) |
| DBSNP | rs267607035 rs1461368206 rs267607036 |
| Subcellular location [CC] | Cytoplasm {ECO:0000305}. |
| Mouse PG classification | NA |
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